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Biosciences, Biotechnology

Biosciences, Biotechnology

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IMBB_researchers_reveal_that_DNA_damage_in_tissue-
22.11.2021
IMBB researchers reveal that DNA damage in tissue-infiltrating macrophages triggers an exosome-based metabolic reprogramming leading to chronic inflammation.
Aging, Biology & Biotechnology, Cells, DNA, Health, Publication

Research carried out at the Institute of Molecular Biology and Biotechnology (IMBB) of FORTH, provides evidence that persistent DNA damage triggers an exosome-based, metabolic reprogramming that leads to chronic inflammation and tissue pathology in DNA repair-deficient progeroid syndromes and likely also during aging.

Scientists_uncover_the_role_of_DNA_base_excision_r
07.09.2021
Scientists uncover the role of DNA base excision repair in the pathogenesis of Parkinsonʼs disease
Aging, Biosciences, Cells, Disease, DNA, Health, Neurons, Parkinson's Disease, Publication

The findings of the study, published today in the premier international scientific journal Cell Reports, reveal a novel molecular mechanism underlying the detrimental effects of BER imbalance in the pathogenesis of Parkinson’s disease.

Cardiotoxicity,_as_a_side_effect_of_breast_cancer_
30.07.2021
Cardiotoxicity, as a side effect of breast cancer treatment, at the heart of a new European research project
Cancer, Disease, Funding

The new European research project CARDIOCARE, will focus on the management of the elderly multimorbid patients with breast cancer therapy-induced cardiac toxicity.

Discovery_of_a_new_Protein,_playing_a_key_role_in_
26.05.2021
Discovery of a new Protein, playing a key role in cell function, paves the way for new therapies
Aging, Cancer, Disease, DNA, Genetics, Proteins, Publication

Research carried out at the Institute of Molecular Biology and Biotechnology-FORTH and published today in Nature Communications provides evidence that the XAB2 protein functionally links persistent DNA damage with the core spliceosome and the processing of R-loops, highlighting the functional links between genome maintenance and the splicing machinery in development or disease.

Research_and_Innovation_for_prevention_of_cognitiv
22.03.2021
Research and Innovation for prevention of cognitive decline: the kick-off meeting of LETHE project

LETHE (λήθη) – A personalized prediction and intervention model for early detection and reduction of risk factors causing dementia, based on AI and distributed Machine Learning

A_new_international_research_programme_targeting_t
17.11.2020
A new international research programme targeting the accurate prognosis and precise treatment of prostate cancer will be coordinated by FORTH

Α big European research project on developing new software tools for the accurate prognosis and precise treatment of prostate cancer, will be coordinated by Prof. Manolis Tsiknakis, Affiliated Professor at the Institute of Computer Science (ICS) of FORTH.