IMBB researchers uncover a novel mechanism that controls longevity by coordinating mitochondrial biogenesis and turnover in the cell, during ageingResearch at the Institute of Molecular Biology and Biotechnology, published today in the premier international scientific journal Nature, reveals an intricate molecular mechanism that coordinates the biogenesis and selective elimination of mitochondria, to regulate cellular energy homeostasis during ageing.

Research on Nucleotide Excision Repair earns George Garinis an ERC Consolidator GrantGeorge Garinis, a Professor at the Department of Biology, University of Crete and an affiliated group leader at the Foundation for Research and Technology - Hellas (FORTH), has recently been awarded the prestigious European Research Council (ERC) Consolidator Grant for his research proposal titled "Dissecting the Functional Role of Nucleotide Excision Repair in Mammals-DeFiNER."

Magnetic materials pushing the frontiers of medical diagnostics A state-of-the art approach to enhance the resolution of non-invasive medical diagnosis techniques is to utilize nano-size materials which are delivered at the regions of interest and allow improved tissue contrast. For such applications, magnetic iron oxides are emerging as promising probes in the diagnosis of various diseases and especially in the area of magnetic resonance imaging (MRI).

VEGF SIGNALING INTEGRATES THE UPR MACHINERY OF THE ENDOPLASMIC RETICULUM IN PHYSIOLOGIC RESPONSES SUCH AS ANGIOGENESISResearchers at the Department of Biomedical Research IMBB Ioannina revealed that growth factor signaling in cells integrates the response mechanism to the presence of unfolded proteins (Unfolded Protein Response, UPR) in the endoplasmic reticulum (ER). This study shows that ER plays an important role in normal cell functions, such as signaling by growth factors, and is not limited to the adaptation of the cell to stress.