FORTH coalition awarded a “4 Stars” Reference Site status for the Region of Crete in the European Innovation Partnership on Active and Healthy AgeingOn January 17th 2020, the European Commission awarded the coalition of the Foundation for Research and Technology – Hellas (FORTH), led by the Institute of Computer Science, a “4 Stars” Reference Site status, the highest possible ranking in the European Innovation Partnership on Active and Healthy Ageing.

A new icy planet detected in our nearest exoplanetary systemStrong indications for the existence of a second planet in orbit around Proxima Centauri, the nearest star to the Sun, have been recently unveiled by an international team of scientists.

FORTH became a member of the Global Talent Mentoring HubA memorandum of understanding was signed between the Foundation for Research and Technology –Hellas and Regensburg University (Germany), in the framework of the Global Talent Mentoring Hub (GTMH) initiative. GTMH is an excellence‐focused online mentoring platform in STEMM (Science, Technology, Engineering, Mathematics, and Medicine).

New scientific discovery by researchers at FORTH DNA damage triggers metabolic reprogramming, leading to aging Inborn defects in DNA repair mechanisms are associated with cancer, aging but also complex metabolic and endocrine disorders. Integrity of the genome is critical for normal cellular function but the DNA is continually challenged by intrinsic and extrinsic genotoxic factors. To counteract DNA damage, cells have evolved DNA repair mechanisms ensuring that the genome remains functionally intact and is faithfully transmitted to progeny. Nucleotide excision repair (NER) is a major DNA repair mechanism that cells employ to remove a wide class of bulky, DNA-distorting lesions from the genome. The importance of NER defects in man is illustrated by rare syndromes that either show increased cancer predisposition or dramatic features of accelerated aging, including depletion of fat depots. However, with the exception of cancer and aging, the links between defects in NER and the rapid onset of developmental defects in humans are not well understood.